Innovation Update: The Bio-Fermentation Revolution at Dr. TWL®

For years, the skincare industry has operated under a quiet limitation known as the 500 Dalton Rule. This biological law dictates that molecules larger than 500 Daltons cannot effectively penetrate the skin barrier. In simpler terms, this means that many of the world’s most potent botanical ingredients—collagen, peptides, and raw extracts—are physically too large to be absorbed. They sit on the surface of your skin, providing temporary hydration but failing to deliver deep structural change.

Today, Dr.TWL® is proud to announce the official establishment of the Asian Bio-Dermatology Institute, a transnational research body designed specifically to solve this physics problem through the power of fermentation.

Headquartered in Singapore with advanced research divisions in the botanical biotechnology epicenter of China, the Institute marks the most significant evolution in our history. We are moving beyond the original Founders Formula and entering the era of the Bibang Formula ™—a high-precision clinical ecosystem that merges ancient herbal wisdom with futuristic bio-engineering.

The Dr.TWL® Fermentation Engine

At the heart of this expansion is our proprietary Fermentation Engine. Instead of simply mixing raw ingredients, the Institute utilizes a process called Enzymatic Hydrolysis. This bio-fermentation technology acts like a molecular scissor, breaking down powerful botanicals such as Mugwort (Artemisia) and Rice (Oryza Sativa) into micro-molecular weights. By reducing the particle size, we ensure these active compounds can bypass the 500 Dalton barrier, delivering nutrients deep into the dermis where true rejuvenation happens.

This research has culminated in the launch of the Fermentation Facelift ™. This proprietary protocol offers a non-invasive alternative to traditional aesthetic procedures. By relying on the bio-availability of fermented enzymes rather than needles or machines, we are setting a new international standard for skincare efficacy.

The Bibang Formula ™ represents the convergence of our “Seoul-era” research and the rich archives of Asian “Secret Prescriptions” (Bibang), now modernized for the clinical age. We invite you to experience the future of bio-available beauty—where tradition meets technology.